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Article

Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Jan 2010

Limson Melvin V, Sweder Kevin S

Abstract excerpt

The yeast target of rapamycin (Tor) kinases, Tor1 and Tor2, belong to the phosphatidylinositol 3-kinase-related family of proteins, which are involved in the cellular response to DNA damage and changes in nutrient conditions. In contrast to yeast, many eukaryotes possess a single Tor kinase. Regardless of the number of Tor kinases in an organism, two distinct complexes involving Tor proteins exist in eukaryotes,...

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Source

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Identifiers

PMID: 19805410
DOI: 10.1093/toxsci/kfp238
PMCID: PMC2794332

Genes

FPR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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