Article
Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis.
Arthritis research & therapy - 1 Jan 2009
Corcione Anna, Ferlito Francesca, Gattorno Marco, Gregorio Andrea, Pistorio Angela, Gastaldi Roberto, Gambini Claudio, Martini Alberto, Traggiai Elisabetta, Pistoia Vito
Abstract excerpt
INTRODUCTION: In chronic inflammatory disorders, B cells can contribute to tissue damage by autoantibody production and antigen presentation to T cells. Here, we have characterized synovial fluid and tissue B-cell subsets in patients with oligoarticular juvenile idiopathic arthritis (JIA), an issue not addressed before in detail. METHODS: B cells from synovial fluid (SF) and peripheral blood (PB) of 25 JIA...
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