Article
Tumor necrosis factor-alpha gene promoter region polymorphism and the risk of coronary heart disease.
TheScientificWorldJournal - 1 Jan 2013
Asifa Gul Zareen, Liaquat Afrose, Murtaza Iram, Kazmi Syed Ali Raza, Javed Qamar
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF- α ) gene polymorphisms have been implicated in the manifestation of atherosclerosis. Controversy exists regarding the link between the cytokine's variant genotype and CHD among different ethnic groups. There have been fewer studies on the TNF- α gene -1031T>C and -863C>A polymorphisms in relation to CHD. Therefore, the current study was designed to investigate the...
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