Article
TNF-alpha -308G>A and IL-6 -174G>C polymorphisms in Tunisian patients with coronary artery disease.
Clinical biochemistry - 1 Sept 2010
Ghazouani Lakhdar, Ben Hadj Khalifa Sonia, Abboud Nesrine, Ben Hamda Khaldoun, Ben Khalfallah Ali, Brahim Nsiri, Almawi Wassim Youssef, Mahjoub Touhami
Abstract excerpt
OBJECTIVE: Our aim was to evaluate the contribution of tumor necrosis factor (TNF)-alpha -308G>A and interleukin (IL)-6 -174G>C gene promoter variants to the presence of coronary artery disease (CAD) in Tunisians. DESIGN AND METHODS: Study subjects comprised 418 angiographically proven CAD patients and 406 age-, gender-, and ethnic origin-matched controls. Genotyping was performed using polymerase chain reaction...
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