Article
Association between the -2518G/A polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and myocardial infarction in Tunisian patients.
Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2008
Jemaa Riadh, Rojbani Hajer, Kallel Amani, Ben Ali Samir, Feki Moncef, Chabrak Sonia, Elasmi Monia, Taieb Samah Haj, Sanhaji Haïfa, Souheil Omar, Mechmeche Rachid, Kaabachi Naziha
Abstract excerpt
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1; gene name CCL2) has been suggested to play an important role in the initiation of atherosclerosis by recruiting monocytes to sites of injured endothelium. Recently, single nucleotide polymorphisms (SNPs) in the MCP-1 regulatory region have been identified. Controversial results regarding the association of the -2518G/A polymorphism of the MCP-1 gene with...
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