Article
TNF-α polymorphisms and coronary artery disease: association study in the Korean population.
Cytokine - 1 Apr 2013
Cho Ho-Chan, Yu Gyeongim, Lee Mi-Young, Kim Hye-Soon, Shin Dong-Hoon, Kim Yoon-Nyun
Abstract excerpt
Coronary artery disease (CAD) results from atherosclerosis, a chronic inflammatory disease mediated in part by proinflammatory cytokines, particularly tumor necrosis factor-α (TNF-α), which is expressed by atherosclerotic plaques. In this study, we investigated whether TNF-α gene promoter polymorphisms affect the incidence of CAD in Koreans by genotyping. 404 Control subjects and 197 patients who previously...
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