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Article

Rapid inexpensive genome-wide association using pooled whole blood.

Genome research - 1 Nov 2009

Craig Jamie E, Hewitt Alex W, McMellon Amy E, Henders Anjali K, Ma Lingjun, Wallace Leanne, Sharma Shiwani, Burdon Kathryn P, Visscher Peter M, Montgomery Grant W, MacGregor Stuart

Abstract excerpt

Genome-wide association studies (GWAS) have now successfully identified important genetic variants associated with many human traits and diseases. The high cost of genotyping arrays in large data sets remains the major barrier to wider utilization of GWAS. We have developed a novel method in which whole blood from cases and controls, respectively, is pooled prior to DNA extraction for genotyping. We demonstrate...

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Identifiers

PMID: 19801603
DOI: 10.1101/gr.094680.109
PMCID: PMC2775600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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