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Article

Program update and novel use of the DESPAIR program to design a genome-wide linkage study using relative pairs.

Human heredity - 1 Jan 2010

Ochs-Balcom Heather M, Guo Xiuqing, Yonebayashi Takashi, Wiesner Georgia, Elston Robert C

Abstract excerpt

DESPAIR (DESign for PAIRs) is a computer program useful for designing a two-stage linkage study using relative pairs for a dichotomous phenotype. It determines the optimal two-stage study design - i.e., for specified power and significance level, how many pairs of relatives should be studied, how...

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PMID: 19797908
DOI: 10.1159/000243153
PMCID: PMC2880734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19797908-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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