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Article

UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans.

The Journal of cell biology - 21 Sept 2009

Sumakovic Marija, Hegermann Jan, Luo Ling, Husson Steven J, Schwarze Katrin, Olendrowitz Christian, Schoofs Liliane, Richmond Janet, Eimer Stefan

Abstract excerpt

Small guanosine triphosphatases of the Rab family regulate intracellular vesicular trafficking. Rab2 is highly expressed in the nervous system, yet its function in neurons is unknown. In Caenorhabditis elegans, unc-108/rab-2 mutants have been isolated based on their locomotory defects. We show that the locomotion defects of rab-2 mutants are not caused by defects in synaptic vesicle release but by defects in...

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Source

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Identifiers

PMID: 19797081
DOI: 10.1083/jcb.200902096
PMCID: PMC2753160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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