Article
UNC-108/Rab2 regulates postendocytic trafficking in Caenorhabditis elegans.
Molecular biology of the cell - 1 Jul 2008
Chun Denise K, McEwen Jason M, Burbea Michelle, Kaplan Joshua M
Abstract excerpt
After endocytosis, membrane proteins are often sorted between two alternative pathways: a recycling pathway and a degradation pathway. Relatively little is known about how trafficking through these alternative pathways is differentially regulated. Here, we identify UNC-108/Rab2 as a regulator of postendocytic trafficking in both neurons and coelomocytes. Mutations in the Caenorhabditis elegans Rab2 gene unc-108,...
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