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Article

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons.

G3 (Bethesda, Md.) - 1 Apr 2026

Oliver Devyn B, Ramachandran Shankar, Biswas Kasturi, Bénard Claire Y, Doitsidou Maria, McKillop Hailey, Genao Noelia, Lemons Michele L, Francis Michael M

Abstract excerpt

A high degree of cell and circuit-specific regulation has presented challenges for efforts to precisely define molecular mechanisms controlling synapse formation and maturation. Here, we pursue an unbiased forward genetic approach to identify Caenorhabditis elegans genes involved in the formation and maturation of cholinergic synaptic connections with GABAergic motor neurons as indicated by the distribution of...

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Identifiers

PMID: 41655250
DOI: 10.1093/g3journal/jkag028
PMCID: PMC13042287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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