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Article

A negatively charged residue in place of histone H3K56 supports chromatin assembly factor association but not genotoxic stress resistance.

DNA repair - 3 Dec 2009

Erkmann Judith A, Kaufman Paul D

Abstract excerpt

In fungal species, lysine 56 of newly synthesized histone H3 molecules is modified by the acetyltransferase Rtt109, which promotes resistance to genotoxic agents. To further explore how H3 K56ac contributes to genome stability, we conducted screens for suppressors of the DNA damage sensitivity of budding yeast rtt109 Delta mutants. We recovered a single extragenic suppressor mutation that efficiently restored...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19796999
DOI: 10.1016/j.dnarep.2009.09.004
PMCID: PMC2787813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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