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Article

Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers.

The Journal of biological chemistry - 30 Mar 2012

Fazly Ahmed, Li Qing, Hu Qi, Mer Georges, Horazdovsky Bruce, Zhang Zhiguo

Abstract excerpt

The yeast histone chaperone Rtt106 is involved in de novo assembly of newly synthesized histones into nucleosomes during DNA replication and plays a role in regulating heterochromatin silencing and maintaining genomic integrity. The interaction of Rtt106 with H3-H4 is modulated by acetylation of H3 lysine 56 catalyzed by the lysine acetyltransferase Rtt109. Using affinity purification strategies, we demonstrate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22337870
DOI: 10.1074/jbc.M112.347450
PMCID: PMC3322881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers.PMID 22337870Read ↗

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