Article
Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations.
Journal of autoimmunity - 1 Mar 2010
Gourh Pravitt, Agarwal Sandeep K, Martin Ezequiel, Divecha Dipal, Rueda Blanca, Bunting Haley, Assassi Shervin, Paz Gene, Shete Sanjay, McNearney Terry, Draeger Hilda, Reveille John D, Radstake T R D J, Simeon Carmen P, Rodriguez Luis, Vicente Esther, Gonzalez-Gay Miguel A, Mayes Maureen D, Tan Filemon K, Martin Javier, Arnett Frank C
Abstract excerpt
OBJECTIVE: Genetic studies in the systemic sclerosis (SSc), an autoimmune disease that clinically manifests with dermal and internal organ fibrosis and small vessel vasculopathy, have identified multiple susceptibility genes including HLA-class II, PTPN22, IRF5, and STAT4 which have also been associated with other autoimmune diseases, such as systemic lupus erythematosus (SLE). These data suggest that there are...
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