Article
ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.
American journal of ophthalmology - 1 Feb 2011
Sobrin Lucia, Reynolds Robyn, Yu Yi, Fagerness Jesen, Leveziel Nicolas, Bernstein Paul S, Souied Eric H, Daly Mark J, Seddon Johanna M
Abstract excerpt
PURPOSE: To determine if genetic variants that have been associated with age-related macular degeneration (AMD) have a differential effect on the risk of choroidal neovascularization (CNV) and geographic atrophy. DESIGN: Genetic association study. METHODS: SETTING: Multicenter study. STUDY POPULATION: Seven hundred forty-nine participants with geographic atrophy and 3209 participants with CNV were derived from 4...
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