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Article

Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007

Shuler R Keith, Hauser Michael A, Caldwell Jennifer, Gallins Paul, Schmidt Silke, Scott William K, Agarwal Anita, Haines Jonathan L, Pericak-Vance Margaret A, Postel Eric A

Abstract excerpt

OBJECTIVE: To compare phenotypes of 2 age-related macular degeneration (AMD) susceptibility genes: LOC387715 and complement factor H (CFH). METHODS: Phenotypes of 755 AMD cases were characterized. The number of LOC387715 (T allele at rs10490924, or A69S) and CFH (T1277C at rs1061170, or Y402H) risk alleles were determined in each case. Individuals were divided into 5 groups by genotype: group 1, LOC-/- CFH-/-;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Choroidal Neovascularization
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Source

Identifiers

PMID: 17210853
DOI: 10.1001/archopht.125.1.63

Genes

CFH

Variants

rs10490924
rs10490924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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