Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.

Investigative ophthalmology & visual science - 1 Nov 2012

Sundaresan Periasamy, Vashist Praveen, Ravindran Ravilla D, Shanker Ashwini, Nitsch Dorothea, Nonyane Bareng A S, Smeeth Liam, Chakravarthy Usha, Fletcher Astrid E

Abstract excerpt

PURPOSE: Association between genetic variants in complement factor H (CFH), factor B (CFB), component 2 (C2), and in the ARMS2/HTRA1 region with age-related macular degeneration (AMD) comes mainly from studies of European ancestry and case-control studies of late-stage disease. We investigated associations of both early and late AMD with these variants in a population-based study of people aged 60 years and older...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C2
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Temperature Requirement A Serine Peptidase 1

Share to Macular Degeneration

Share to Prevalence

Share to Proteins

Share to Serine Endopeptidases

Source

Open in PubMed Open full text

Identifiers

PMID: 23060141
DOI: 10.1167/iovs.12-10073
PMCID: PMC3490538

Genes

ARMS2
HTRA1
CFB
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.PMID 23060141Read ↗

Genetic risk factors for late age-related macular degeneration in India.Semantic proximity Read ↗

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.Semantic proximity Read ↗

Impact of age-related maculopathy susceptibility 2, high-temperature requirement A serine peptidase 1, and complement factor H genetic variants on clinical phenotypes of age-related macular degeneration.Semantic proximity Read ↗

C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration.Semantic proximity Read ↗

The molecular genetic basis of age-related macular degeneration: an overview.Semantic proximity Read ↗

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in CFH, ARMS2 and HTRA1 genes with risk of age-related macular degeneration in Egyptian patients.Semantic proximity Read ↗

Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.Semantic proximity Read ↗

Genetic and environmental risk factors for age-related macular degeneration in persons 90 years and older.Semantic proximity Read ↗

No association of age-related maculopathy susceptibility protein 2/HtrA serine peptidase 1 or complement factor H polymorphisms with early age-related maculopathy in a Chinese cohort.Semantic proximity Read ↗

Association analysis of CFH and ARMS2 gene polymorphisms in a Brazilian cohort with age-related macular degeneration.Semantic proximity Read ↗

Association between Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular DegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.