Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration.

doi:10.1016/j.ophtha.2007.06.021

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Article

Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration.

Ophthalmology - 1 Mar 2008

Shuler R Keith, Schmidt Silke, Gallins Paul, Hauser Michael A, Scott William K, Caldwell Jennifer, Agarwal Anita, Haines Jonathan L, Pericak-Vance Margaret A, Postel Eric A

Abstract excerpt

OBJECTIVE: To examine phenotypes of age-related macular degeneration (AMD) patients with the complement factor H (CFH) variant (Y402H, C allele at rs1061170). DESIGN: Clinic-based case series study. PARTICIPANTS: The data set contained a total of 956 unrelated cases of AMD. METHODS: Age-related macular degeneration phenotypes of 796 carriers of the CFH Y402H variant were compared with the AMD phenotypes of 160...

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PMID: 18067970
DOI: 10.1016/j.ophtha.2007.06.021

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