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Article

Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes.

Journal of cellular physiology - 1 Jan 2010

Heywood Hannah K, Lee David A

Abstract excerpt

Autologous chondrocyte implantation requires a phase of in vitro cell expansion, achieved by monolayer culture under atmospheric oxygen levels. Chondrocytes reside under low oxygen conditions in situ and exhibit a glycolytic metabolism. However, oxidative phosphorylation rises progressively durin...

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Identifiers

PMID: 19795395
DOI: 10.1002/jcp.21946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19795395-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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