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Article

Oxygen tension is a determinant of the matrix-forming phenotype of cultured human meniscal fibrochondrocytes.

PloS one - 1 Jan 2012

Adesida Adetola B, Mulet-Sierra Aillette, Laouar Leila, Jomha Nadr M

Abstract excerpt

BACKGROUND: Meniscal cartilage displays a poor repair capacity, especially when injury is located in the avascular region of the tissue. Cell-based tissue engineering strategies to generate functional meniscus substitutes is a promising approach to treat meniscus injuries. Meniscus fibrochondrocytes (MFC) can be used in this approach. However, MFC are unable to retain their phenotype when expanded in culture. In...

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Identifiers

PMID: 22720095
DOI: 10.1371/journal.pone.0039339
PMCID: PMC3376130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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