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Article

Oxygen and reactive oxygen species in cartilage degradation: friends or foes?

Osteoarthritis and cartilage - 1 Aug 2005

Henrotin Y, Kurz B, Aigner T

Abstract excerpt

OBJECTIVES: This review is focused on the influence of oxygen and derived reactive species on chondrocytes aging, metabolic function and chondrogenic phenotype. METHODS: A systematic computer-aided search of the Medline database. RESULTS: Articular cartilage is an avascular tissue, and consequently oxygen supply is reduced. Although the basal metabolic functions of the cells are well adapted to hypoxia, the...

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Source

Identifiers

PMID: 15936958
DOI: 10.1016/j.joca.2005.04.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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