Article
Oxygen and reactive oxygen species in articular cartilage: modulators of ionic homeostasis.
Pflugers Archiv : European journal of physiology - 1 Jan 2008
Gibson J S, Milner P I, White R, Fairfax T P A, Wilkins R J
Abstract excerpt
Articular cartilage is an avascular tissue dependent on diffusion mainly from synovial fluid to service its metabolic requirements. Levels of oxygen (O(2)) in the tissue are low, with estimates of between 1 and 6%. Metabolism is largely, if not entirely, glycolytic, with little capacity for oxida...
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