Article
A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.
Postgraduate medical journal - 1 Oct 2009
Young R P, Hopkins R J, Hay B A, Epton M J, Mills G D, Black P N, Gardner H D, Sullivan R, Gamble G D
Abstract excerpt
BACKGROUND: Epidemiological and family studies suggest that lung cancer results from the combined effects of age, smoking and genetic factors. Chronic obstructive pulmonary disease (COPD) is also an independent risk factor for lung cancer and coexists in 40-60% of lung cancer cases. METHODS: In a two-stage case-control association study, genetic markers associated with either susceptibility or protection against...
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