Article
Lung cancer susceptibility model based on age, family history and genetic variants.
PloS one - 1 Jan 2009
Young Robert P, Hopkins Raewyn J, Hay Bryan A, Epton Michael J, Mills Graham D, Black Peter N, Gardner Heather D, Sullivan Richard, Gamble Gregory D
Abstract excerpt
BACKGROUND: Epidemiological and pedigree studies suggest that lung cancer results from the combined effects of age, smoking, impaired lung function and genetic factors. In a case control association study of healthy smokers and lung cancer cases, we identified genetic markers associated with either susceptibility or protection to lung cancer. METHODOLOGY/PRINCIPAL FINDINGS: We screened 157 candidate single...
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