Article
Prediction of lung cancer risk in a Chinese population using a multifactorial genetic model.
BMC medical genetics - 10 Dec 2012
Li Huan, Yang Lixin, Zhao Xueying, Wang Jiucun, Qian Ji, Chen Hongyan, Fan Weiwei, Liu Hongcheng, Jin Li, Wang Weimin, Lu Daru
Abstract excerpt
BACKGROUND: Lung cancer is a complex polygenic disease. Although recent genome-wide association (GWA) studies have identified multiple susceptibility loci for lung cancer, most of these variants have not been validated in a Chinese population. In this study, we investigated whether a genetic risk score combining multiple. METHODS: Five single-nucleotide polymorphisms (SNPs) identified in previous GWA or large...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
