Article
A rigorous and comprehensive validation: common genetic variations and lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2010
Yang Ping, Li Yafei, Jiang Ruoxiang, Cunningham Julie M, Li Yan, Zhang Fang, de Andrade Mariza
Abstract excerpt
BACKGROUND: Multiple recent genome-wide studies of single nucleotide polymorphisms (SNP) reported associations between candidate chromosome loci and lung cancer susceptibility. We evaluated five of the top candidate SNPs (rs402710, rs2736100, rs4324798, rs16969968, and rs8034191) for their effects on lung cancer risk and overall survival. METHODS: Over 1,700 cases and 2,200 controls were included in this study....