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Article

Association between MDR1/CYP3A4/OPRM1 gene polymorphisms and the post-caesarean fentanyl analgesic effect on Chinese women.

Gene - 30 Jun 2018

Zhang Jingliang, Zhang Li, Zhao Xia, Shen Sheliang, Luo Xiaopan, Zhang Yunlong

Abstract excerpt

OBJECTIVE: Our study aimed to evaluate the association between the multidrug resistance 1 (MDR1)/cytochrome P450 3A4 (CYP3A4)/μ-opioid receptor (OPRM1) gene polymorphisms and the post-caesarean analgesic effect of fentanyl on Chinese women. METHODS: We recruited 240 patients who received lower segment caesarean section surgeries. Sanger sequencing was used to analyze the MDR11236C > T/CYP3A4*1G/OPRM1A118G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29601950
DOI: 10.1016/j.gene.2018.03.081

Genes

OPRM1

Variants

Provenance

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