Article
[Detection of cytochrome P450 3A4 gene polymorphism guides for labor analgesia with sufentanil medication].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Aug 2015
Chi Li-qun, Lu Xin, Wang Lei, Liu Shu-ping, Ding Nan, Zhang Hong-ying, E Wen
Abstract excerpt
OBJECTIVE: To investigate the relationship between single nucleotide polymorphisms (SNPs) of cytochrome P450 (CYP450) 3A4 rs2242480 and inter-individual differences of sufentanil consumption in accouchement sans douleur. METHODS: A total of 131 parturient women were collected. According to the distribution of genotypes and allele frequencies of rs2242480, the doses of sufentanil were individually designed. CC...
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