Article
Genetic variants in mitochondrial tRNA genes are associated with essential hypertension in a Chinese Han population.
Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2009
Zhu Hai-Yan, Wang Shi-Wen, Liu Li, Chen Rui, Wang Lin, Gong Xing-Lai, Zhang Min-Lu
Abstract excerpt
BACKGROUND: Of multiple factors contributing to essential hypertension, mitochondrial variants exhibited the trends for serving as molecular and genetic markers for the disease in last five years. However, previous studies focused on African-American or Caucasian pedigrees, knowledge of mitochondrial tRNA genes and population-based Chinese hypertensives were limited. METHODS: We performed sequence analysis in...
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