Article
HIV-1 compartmentalization in diverse leukocyte populations during antiretroviral therapy.
Journal of leukocyte biology - 1 Sept 2004
Potter Simon J, Lemey Philippe, Achaz Guillaume, Chew Choo Beng, Vandamme Anne-Mieke, Dwyer Dominic E, Saksena Nitin K
Abstract excerpt
CD4+ T lymphocytes are the primary target of human immunodeficiency virus type 1 (HIV-1), but there is increasing evidence that other immune cells in the blood, including CD8+ T lymphocytes and monocytes, are also productively infected. The extent to which these additional cellular reservoirs contribute to ongoing immunodeficiency and viral persistence during therapy remains unclear. In this study, we conducted a...
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