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Article

Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer.

Cancer causes & control : CCC - 1 Nov 2009

Tsilidis Konstantinos K, Helzlsouer Kathy J, Smith Michael W, Grinberg Victoriya, Hoffman-Bolton Judith, Clipp Sandra L, Visvanathan Kala, Platz Elizabeth A

Abstract excerpt

OBJECTIVE AND METHODS: The association of 17 candidate single nucleotide polymorphisms (SNPs) in IL10 and other immune response genes (CRP, TLR4, IL6, IL1B, IL8, TNF, RNASEL) and genes related to obesity (PPARG, TCF7L2, ADIPOQ, LEP) with colorectal cancer was investigated. Haplotype tagging SNPs were chosen for IL10, CRP, and TLR4. Incident colorectal cancer cases (n = 208) and matched controls (n = 381) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19760027
DOI: 10.1007/s10552-009-9427-7
PMCID: PMC4119174

Genes

CRP
TLR4
ADIPOQ
LEP
PPARG
RNASEL
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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