Article
Significance of -1082A/G polymorphism of IL10 gene for progression of colorectal cancer and IL-10 expression.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014
Miteva Lyuba D, Stanilov Noyko S, Deliysky Tashko S, Stanilova Spaska A
Abstract excerpt
The role of functional polymorphism within IL10 (rs1800896) in colorectal cancer (CRC) still remains elusive. The aim of present study was to investigate the significance of -1082A/G polymorphism in IL10 on CRC risk, progression, and overall survival in a cohort of Bulgarian patients. Also, a functional role of this polymorphism on systemic and local level of IL10 mRNA quantity and serum IL-10 level was explored....
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