Article
Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.
International journal of cancer - 1 Jun 2011
Slattery Martha L, Curtin Karen, Poole Elizabeth M, Duggan David J, Samowitz Wade S, Peters Ulrike, Caan Bette J, Potter John D, Ulrich Cornelia M
Abstract excerpt
C-reactive protein (CRP), a biomarker of inflammation, has been shown to be influenced by genetic variation in the CRP gene. In this study, we test the hypothesis that genetic variation in CRP influences both the risk of developing colon and rectal cancer and survival. Two population-based studies of colon cancer (n = 1,574 cases, 1,970 controls) and rectal (n = 791 cases, 999 controls) were conducted. We...
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