Meta-analysis of epidemiological studies of  association of two polymorphisms in the interleukin-10 gene promoter and colorectal  cancer risk.

doi:10.4238/2012.September.25.7

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Article

Meta-analysis of epidemiological studies of association of two polymorphisms in the interleukin-10 gene promoter and colorectal cancer risk.

Genetics and molecular research : GMR - 25 Sept 2012

Zhang Y M, Zhou X C, Xu Z, Tang C J

Abstract excerpt

In order to make a comprehensive assessment of the potential association between two genetic variants in the IL-10 gene promoter, -1082 A>G (rs1800896) and -592 C>A (rs1800872), and colorectal cancer (CRC) risk, we conduced a meta-analysis of seven epidemiological studies, which included 1469 colorectal cancer cases and 2566 controls. Neither of the two polymorphisms had any association with increased CRC risk in...

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PMID: 23079832
DOI: 10.4238/2012.September.25.7

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