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Article

Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk.

Molecular carcinogenesis - 1 Oct 2018

Huang Brian Z, Tsilidis Konstantinos K, Smith Michael W, Hoffman-Bolton Judith, Visvanathan Kala, Platz Elizabeth A, Joshu Corinne E

Abstract excerpt

We previously investigated the association between single nucleotide polymorphisms (SNPs) in genes related to obesity and inflammation and colorectal cancer in the CLUE II cohort. However, the relationships between these SNPs and colorectal adenomas have not been well evaluated. In a nested case-control study of 135 incident adenoma cases and 269 matched controls in the CLUE II cohort (1989-2000), we genotyped 17...

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Identifiers

PMID: 29802748
DOI: 10.1002/mc.22842
PMCID: PMC6697114

Genes

CRP
TLR4
ADIPOQ
LEP
PPARG
RNASEL
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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