Article
Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer.
Cancer research - 1 Jul 2003
Landi Stefano, Moreno Victor, Gioia-Patricola Lydie, Guino Elisabeth, Navarro Matilde, de Oca Javier, Capella Gabriel, Canzian Federico
Abstract excerpt
Animal models and epidemiological observations suggest that a continuous inflammatory condition predisposes to colorectal cancer (CRC), but the roles of different elements participating in inflammatory responses have been little investigated in relation to CRC. We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-174 G>C), IL8 (-251T>A), tumor necrosis factor alpha...
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