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Article

Alteration of alpha 1 Na+,K(+)-ATPase 86Rb+ influx by a single amino acid substitution.

Science (New York, N.Y.) - 31 Aug 1990

Herrera V L, Ruiz-Opazo N

Abstract excerpt

The sodium- and potassium-dependent adenosine triphosphatase (Na+,K(+)-ATPase) maintains the transmembrane Na+ gradient to which is coupled all active cellular transport systems. The R and S alleles of the gene encoding the Na+,K(+)-ATPase alpha 1 subunit isoform were identified in Dahl salt-resistant (DR) and Dahl salt-sensitive (DS) rats, respectively. Characterization of the S allele-specific Na+,K(+)-ATPase...

Topics

Amino Acid Sequence
Animals
Cell Membrane
Kidney
Kinetics
Molecular Sequence Data
Mutation
Polymorphism, Restriction Fragment Length
Protein Conformation
Rats
Rats, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rubidium

Rubidium Radioisotopes

Sodium-Potassium-Exchanging ATPase

Source

Identifiers

PMID: 1975705
DOI: 10.1126/science.1975705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1975705-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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