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A COL2A1 gene polymorphism is related with advanced stages of osteoarthritis of the knee in Mexican Mestizo population.

Rheumatology international - 1 Jun 2010

Gálvez-Rosas Arturo, González-Huerta Celia, Borgonio-Cuadra Verónica Marusa, Duarte-Salazár Carolina, Lara-Alvarado Lorena, de los Angeles Soria-Bastida María, Cortés-González Socorro, Ramón-Gallegos Eva, Miranda-Duarte Antonio

Abstract excerpt

Primary osteoarthritis (OA) is a multifactorial disease with several genetics factors involved. The COL2A1 gene is of particular interest because it encodes for the most abundant protein in articular cartilage. The aim was to evaluate the association of COL2A1 gene polymorphism with OA of the knee in Mexican Mestizo patients. A case-control study was conducted; cases comprised patients with a radiologic scoring >...

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PMID: 19756630
DOI: 10.1007/s00296-009-1091-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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