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Article

DNA methyltransferase genes polymorphisms are associated with primary knee osteoarthritis: a matched case-control study.

Rheumatology international - 1 Apr 2020

Miranda-Duarte Antonio, Borgonio-Cuadra Verónica Marusa, González-Huerta Norma Celia, Rojas-Toledo Emma Xochitl, Ahumada-Pérez Juan Francisco, Sosa-Arellano Matvey, Morales-Hernández Eugenio, Pérez-Hernández Nonanzit, Rodríguez-Pérez José Manuel

Abstract excerpt

DNA methylation is an epigenetic mechanism involved in the development of primary osteoarthritis (OA). The association between DNA methyltransferases (DNMTs) genes polymorphisms and diseases in which DNA methylation plays a role in their pathogenesis has been described (e.g., cancer); however, its relationship with OA has not been investigated. The aim of this study was to analyze the association between DNMT1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31713648
DOI: 10.1007/s00296-019-04474-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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