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Article

D14 repeat polymorphism of the asporin gene is associated with primary osteoarthritis of the knee in a Mexican Mestizo population.

International journal of rheumatic diseases - 1 Dec 2017

González-Huerta Norma Celia, Borgonio-Cuadra Verónica Marusa, Zenteno Juan Carlos, Cortés-González Socorro, Duarte-Salazar Carolina, Miranda-Duarte Antonio

Abstract excerpt

BACKGROUND: Asporin is a novel extracellular matrix protein (ECM) with an important role in the development of osteoarthritis (OA), because it has been reported that functional polymorphisms in the aspartic acid repeat (D) of the asporin gene (ASPN) are associated with susceptibility to OA. AIM: This study was planned to investigate the association of the ASPN polymorphism with primary OA of the knee in a Mexican...

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Source

Identifiers

PMID: 26620055
DOI: 10.1111/1756-185X.12797

Genes

ASPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

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D14 repeat polymorphism of the asporin gene is associated with primary osteoarthritis of the knee in a Mexican Mestizo population.PMID 26620055Read ↗

Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population.Semantic proximity Read ↗

Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis.Semantic proximity Read ↗

Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese.Semantic proximity Read ↗

A meta-analysis of the relationship between aspartic acid (D)-repeat polymorphisms in asporin and osteoarthritis susceptibility.Semantic proximity Read ↗

Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population.Semantic proximity Read ↗

[Asporin, a susceptibility gene for osteoarthritis].Semantic proximity Read ↗

Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians.Semantic proximity Read ↗

Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.Semantic proximity Read ↗

Investigation of the asporin gene polymorphism as a risk factor for knee osteoarthritis in Iran.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of asporin (ASPN) and BMP5 with the risk of knee osteoarthritis in a Chinese Han population.Semantic proximity Read ↗

Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians.Semantic proximity Read ↗

Meta-analysis of association between the ASPN D-repeat and osteoarthritis.Semantic proximity Read ↗

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