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Article

Analysis of Polymorphisms in the MATN3 and DOT1L Genes and CTX-II Urinary Levels in Patients with Knee Osteoarthritis in a Northeast Mexican-Mestizo Population.

Genetic testing and molecular biomarkers - 1 Feb 2020

García-Alvarado Francisco J, Delgado-Aguirre Héctor A, Rosales-González Manuel, González-Martínez Marisela Del R, Ruiz-Flores Pablo, González-Galarza Faviel F, Arellano Perez Vertti Ruben Daniel

Abstract excerpt

Aims: To investigate the possible roles of the single nucleotide polymorphisms (SNPs) MATN3 (rs77245812) and DOT1L (rs12982744) with susceptibility to knee osteoarthritis (KOA) among mestizos from the northeast region of Mexico. In addition, we analyzed the relationship of their urinary levels of carboxy terminal telopeptide of collagen type II (CTX-II) and the radiological grade of disease. Materials and...

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Source

Identifiers

PMID: 31999490
DOI: 10.1089/gtmb.2019.0179

Genes

DOT1L
MATN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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