Article
Adjacent genes, for COL2A1 and the vitamin D receptor, are associated with separate features of radiographic osteoarthritis of the knee.
Arthritis and rheumatism - 1 Jul 2000
Uitterlinden A G, Burger H, van Duijn C M, Huang Q, Hofman A, Birkenhäger J C, van Leeuwen J P, Pols H A
Abstract excerpt
OBJECTIVE: To study the association of the COL2A1 genotype, in relation to the vitamin D receptor (VDR) genotype, with features of radiographic osteoarthritis (ROA) in a population of elderly men and women. METHODS: In this cross-sectional study, we analyzed a population-based sample of 851 men and women ages 55-80 years from a large cohort study, the Rotterdam Study. We determined the prevalence of ROA of the...
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