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Article

The therapeutic effect of bone marrow-derived liver cells in the phenotypic correction of murine hemophilia A.

Blood - 12 Nov 2009

Yadav Neelam, Kanjirakkuzhiyil Sumod, Kumar Suresh, Jain Manish, Halder Ashutosh, Saxena Renu, Mukhopadhyay Asok

Abstract excerpt

The transdifferentiation of bone marrow cells (BMCs) into hepatocytes has created enormous interest in applying this process to the development of cellular medicine for degenerative and genetic diseases. Because the liver is the primary site of factor VIII (FVIII) synthesis, we hypothesized that the partial replacement of mutated liver cells by healthy cells in hemophilia A mice could manage the severity of the...

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Identifiers

PMID: 19752394
DOI: 10.1182/blood-2009-02-202788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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