Transplanted endothelial cells repopulate the liver endothelium and correct the phenotype of hemophilia A mice.

Abstract excerpt

Transplantation of healthy cells to repair organ damage or replace deficient functions constitutes a major goal of cell therapy. However, the mechanisms by which transplanted cells engraft, proliferate, and function remain unknown. To investigate whether host liver sinusoidal endothelium could be replaced with transplanted liver sinusoidal endothelial cells, we developed an animal model of tissue replacement that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endothelial Cells
• Share to Factor VIII