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Article

Persistence of a chimerical phenotype after hepatocyte differentiation of human bone marrow mesenchymal stem cells

16 Jan 2008

Abstract excerpt

OBJECTIVES: Recent studies have suggested the potential of mesenchymal stem cells (MSCs) to differentiate into a hepatocyte-like lineage. Here, we evaluate the efficacy of hepatocyte differentiation of MSCs by studying acquisition of hepatocyte-like features together with alteration of the native mesenchymal phenotype. MATERIAL AND METHODS: In vitro, we have investigated protein and mRNA level expression of...

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PMID: 18211285
DOI: 10.1111/j.1365-2184.2007.00507.x

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