Article
Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells.
Stem cell research & therapy - 8 Jul 2015
Kochat Veena, Kanjirakkuzhiyil Sumod, Baligar Prakash, Nagarajan Perumal, Mukhopadhyay Asok
Abstract excerpt
INTRODUCTION: Cell replacement therapy may be considered as an alternate approach to provide therapeutic dose of plasma factor VIII (FVIII) in patients with hemophilia A (HA). However, immune rejection limits the use of allogeneic cells in this mode of therapy. Here, we have examined the role of...
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