Article
A subpopulation of bone marrow cells depleted by a novel antibody, anti-Liv8, is useful for cell therapy to repair damaged liver.
Biochemical and biophysical research communications - 23 Jan 2004
Yamamoto Naoki, Terai Shuji, Ohata Shinya, Watanabe Tomomi, Omori Kaoru, Shinoda Koh, Miyamoto Koji, Katada Toshiaki, Sakaida Isao, Nishina Hiroshi, Okita Kiwamu
Abstract excerpt
We previously reported a new in vivo model named as "GFP/CCl(4) model" for monitoring the transdifferentiation of green fluorescent protein (GFP) positive bone marrow cell (BMC) into albumin-positive hepatocyte under the specific "niche" made by CCl(4) induced persistent liver damage, but the subpopulation which BMCs transdifferentiate into hepatocytes remains unknown. Here we developed a new monoclonal antibody,...
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