Article
GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Antúnez Carmen, Boada Mercé, López-Arrieta Jesús, Ramirez-Lorca Reposo, Hernández Isabel, Marín Juan, Martínez-Lage Pablo, González-Pérez Antonio, Jorge Galan José, Gayán Javier, Real Luis M, Ruiz Agustín
Abstract excerpt
GOLPH2 gene SNP variants Rs10868366 and Rs7019241 were reported to decrease the risk of Alzheimer's disease in a recent Whole Genome Association Study. We have investigated these genetic variants in 2470 individuals from Spain to conduct an independent replication study of the proposed SNP markers. We found no evidence of association between GOLPH2 markers and susceptibility to Alzheimer's disease in our series....
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