Article
HSPG2 gene C/A polymorphism does not confer susceptibility to Alzheimer's disease in Chinese.
Dementia and geriatric cognitive disorders - 1 Jan 2007
Wang Binbin, Jin Feng, Yang Ze, Lu Zeping, Zheng Chenguang, Wang Li
Abstract excerpt
Human HSPG2 participates in the formation of amyloid and tau aggregation in Alzheimer's disease (AD). HSPG2 gene is located on a susceptibility region to late-onset AD (LOAD), and considered as a candidate gene for LOAD because of its function and location. We performed an association study between the HSPG2 BamH I polymorphism C/A of intron 6 and LOAD on 104 patients and 127 healthy controls of Chinese origin....
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