No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.

doi:10.1002/humu.20990

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Article

No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.

Human mutation - 1 Apr 2009

Sleegers Kristel, Brouwers Nathalie, Bettens Karolien, Engelborghs Sebastiaan, van Miegroet Helen, De Deyn Peter P, Van Broeckhoven Christine

Abstract excerpt

A non-synonymous polymorphism, rs2986017 (p.P86L), in the newly characterized calcium homeostasis modulator 1 (CALHM1) gene located in the Alzheimer dementia (AD) linkage region on 10q24.33, was reported to increase risk of AD, and affect calcium homeostasis and amyloid beta accumulation. We aimed to investigate the association between this functional polymorphism and AD in an independent study population. We...

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Identifiers

PMID: 19191332
DOI: 10.1002/humu.20990

Genes

CALHM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.PMID 19191332Read ↗

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Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

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CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease.Semantic proximity Read ↗

Lack of implication for CALHM1 P86L common variation in Italian patients with early and late onset Alzheimer's disease.Semantic proximity Read ↗

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.Semantic proximity Read ↗

Calcium homeostasis modulator 1 gene P86L polymorphism and the risk for alzheimer's disease: A meta-analysis.Semantic proximity Read ↗

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